Informatics Publishing Limited

B. Roge Ashish ¹, S. Sakhare Ram ¹, R. L. Bakal ¹, M. A. Channawar ¹, B. V. Bakde ¹, S. R. Gawande ¹, A. V. Chandewar ¹

Affiliations
1 P. Wadhwani College of Pharmacy, Yavatmal, IN

Abstract

Transdermal drug delivery system is emerging system as compaired to oral and parentral.in TDDS, patch system was developed to control the release of drug. Conventional transdermal drug delivery system achieved advantages over the oral and parenteral. Consequently a number of vesicular drug delivery systems such as liposomes, niosomes were been developed as novel transdermal drug delivery system. Firstly, it delivers the drug at a rate directed by the needs of the body, over the period of treatment. Secondly, it channel the active entity to the site of action. However, TDDS has limited market success due to the barrier properties of the Stratum Corneum and stability of formulation. ethosomes is better achievement in vesicular drug delivery system, helpful to achieve goal needed by NTDDS. Ethosomes are noninvasive delivery carriers that enable drugs to reach the deep skin layers and/or the systemic circulation. This review focus on introduction, mechanism of penetration, method of preparation, methods of characterization and application in the field.

Keywords

TDDS, CTDDS, NTDDS, Stratum Corneum , Vesicular Drug Delivery System, Ethosomes.

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S. R. Gawande ¹, A. V. Chandewar ¹

Affiliations
1 P. Wadhwani College of Pharmacy, Yavatmal, MS, IN

Abstract

Oral solid dosage form are more popular than other dosage form but suffer from problems like taste, solubility, bioavailability; so patient compliance. To improve patient compliance, melt in mouth tablets have emerged as an alternative to conventional oral dosage form. The aim is to provide the tablet that quickly melts upon contact with saliva and also provides a good mouthfeel.

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